Empagliflozin

What is it?

Composition

The composition of Empagliflozin is presented in the form of an active component and a number of additional components that ensure its absorption and assimilation by the body. The main active ingredient is the empagliflozin molecule itself. In combination with it, the tablet contains various auxiliary substances that maintain the stability and effectiveness of the drug.

• Empagliflozin is the main active ingredient responsible for the therapeutic effect.
• Lactose monohydrate is used to achieve the required tablet consistency.
• Magnesium stearate is a lubricant used in tablet production.
• Hydroxypropyl cellulose is a substance used to improve the solubility of the active ingredient.
• Talc is used as an anti-adhesive to prevent the tablet components from sticking together.

These components ensure optimal drug efficacy and patient tolerability, which is extremely important for long-term use.

How to use?

Using Empagliflozin requires strict adherence to the instructions and doctors recommendations to achieve the best results from treatment. This drug is usually taken once a day and can be used regardless of food intake.

1. The tablet should be taken in the morning, which helps maintain optimal sugar levels throughout the day.
2. It is important not to skip doses of the drug, as regularity is the key to successful diabetes control.
3. Blood sugar levels must be monitored regularly, which allows you to adjust therapy if necessary.
4. If any changes in the condition or questions about the use of the drug occur, you should immediately consult a doctor.

This will help maintain a stable state of health and minimize the risks of complications and side effects.

How does it work?

The mechanism of action of Empagliflozin is based on its ability to inhibit sodium-glucose cotransporter 2 (SGLT2) in the proximal tubules of the kidneys. This leads to a decrease in glucose reabsorption in the kidneys and an increase in its excretion in the urine, which in turn helps to lower blood sugar levels. This unique action allows not only to control glucose, but also to help reduce body weight and blood pressure.

In addition to sugar control, Empagliflozin has cardioprotective effects. It significantly reduces the risk of cardiovascular events, including heart attacks and strokes, which makes it especially useful for patients with type 2 diabetes, including those who already have cardiovascular disease. This significant advantage of the drug distinguishes it from other antidiabetic drugs.

Indications

Empagliflozin is used in several clinically important indications. It is primarily used in patients with type 2 diabetes who are unable to achieve optimal blood sugar control with diet and exercise alone. It is also used to reduce the risk of cardiovascular mortality and complications in these patients.

• Treatment of type 2 diabetes in combination with other hypoglycemic agents.
• Prevention of cardiovascular complications in patients with type 2 diabetes and existing cardiovascular disease.
• Reduction in the risk of hospitalization due to heart failure.

These indications make Empagliflozin an important drug in the armamentarium of endocrinologists and cardiologists.

Contraindications

Despite its effectiveness, Empagliflozin is contraindicated in a number of cases in which it can cause harm to the patient. This is especially important to consider for patients with certain kidney diseases and allergies to the components of the drug.

• The presence of severe renal failure or dialysis.
• Allergic reactions to empagliflozin or other components.
• Pregnancy and lactation, especially in the later stages.
• Prohibited for use in chronic alcoholism and drinking large amounts of alcohol.

These contraindications must be taken into account before starting therapy to avoid serious consequences.

Side effects

Despite its high effectiveness, Empagliflozin may cause various side effects. Most of them are mild, but some require immediate medical attention.

• Hypersensitivity reactions, such as urticaria or angioedema.
• Urinary tract infections, manifested as burning or pain.
• Hypoglycemia, if the drug is taken with other hypoglycemic agents.
• Dehydration due to increased diuresis.
• The appearance of ketoacidosis, especially with a low level of carbohydrates in the diet.

If such symptoms occur, it is necessary to seek medical help to adjust the treatment or change the drug.